Dr. Nicole Kozloff is a scientist, child and adolescent psychiatrist and the co-director of the Slaight Family Centre for Youth in Transition at the Centre for Addiction and Mental Health (CAMH). She is also an associate professor in the Department of Psychiatry and the Institute of Health Policy, Management and Evaluation at the University of Toronto. Outside of CAMH, Dr. Kozloff also consults to community agencies providing mental health services to youth. Dr. Kozloff completed her Doctor of Medicine at Queen’s University, residency training in psychiatry and child and adolescent psychiatry at the University of Toronto, and a Master of Science in health policy and management at the Harvard TH Chan School of Public Health. Her work has been funded by the Canadian Institutes of Health Research, Ontario Ministry of Health, Brain & Behavior Research Foundation, SSHRC, Brain Canada, Ontario Brain Institute, University of Toronto, CAMH AFP Innovation Fund and CAMH Foundation, including as a Koerner New Scientist.
Dr. Nicole Kozloff is a scientist, child and adolescent psychiatrist and the co-director of the Slaight Family Centre for Youth in Transition at the Centre for Addiction and Mental Health (CAMH). She is also an associate professor in the Department of Psychiatry and the Institute of Health Policy, Management and Evaluation at the University of Toronto. Outside of CAMH, Dr. Kozloff also consults to community agencies providing mental health services to youth. Dr. Kozloff completed her Doctor of Medicine at Queen’s University, residency training in psychiatry and child and adolescent psychiatry at the University of Toronto, and a Master of Science in health policy and management at the Harvard TH Chan School of Public Health. Her work has been funded by the Canadian Institutes of Health Research, Ontario Ministry of Health, Brain & Behavior Research Foundation, SSHRC, Brain Canada, Ontario Brain Institute, University of Toronto, CAMH AFP Innovation Fund and CAMH Foundation, including as a Koerner New Scientist.
Specialty Care
for Youth Wellness
(SCY-Well)
Youth with multiple mental health conditions and additional complexity tend to experience the greatest mental health burden, yet there are few treatments targeted to them. What is needed is a youth-friendly, standardized
intervention that is informed by those with lived experience, addresses a broad range of needs, and is implementable across different settings.
Specialty Care for Youth Wellness (SCY-Well) is modelled after NAVIGATE, a comprehensive model of care for young people who have experienced psychosis, developed as part of the National Institute of Mental Health’s Recovery After Initial Schizophrenia Episode (RAISE) initiative. NAVIGATE is a model of coordinated specialty care delivered by a team of mental health professionals who help young people work toward their personal goals.
Clinicians, researchers, youth and families with lived experience of mental health conditions have collaborated on adapting the model to meet the needs of this population. SCY-Well provides Individual Therapy, Assessment and Medication Management, Family Education and Support, and Supported Employment and Education to youth aged 14-24 years old and their families.
The model incorporates measurement-based care and shared decision making, is strengths based, and attentive to equity, diversity and inclusion.
SCY-Well is currently being evaluated in a single-arm pilot feasibility study. In the next phase, it will be scaled up and evaluated as a multisite pilot randomized-controlled trial as part of the CALM study. Participants receiving the intervention will be compared to others using statistical methods to balance groups. This is an essential next step to realizing a practical, youth co-developed, evidence-based intervention for youth with multiple mental health conditions and additional complexity.
NAVIGATE
The CALM study is a longitudinal study that will take place over 5 years. The goal is to better understand multiple mental health conditions in children and youth, so that we can improve clinical care for these children and youth in the future. We will do this by collecting large amounts of data from a 3,200 people over time, a strategy that we call a Master Observational Trial (MOT). The MOT will help the CALM network develop future studies, called clinical trials, which will help us develop new treatments and improve care. We will do assessments of mental and physical health, behavior and functioning, and biological/genetic samples to learn how these influence mental health over time. Earlier detection may lead to improved mental health care and quality of life for youth during the transition from childhood and adolescence into early adulthood, and over the longer term.
RAISE
The Deep Phenotyping Cohort is a sub-study of the larger CALM study. The aim of this study is to create a large database that can be used to answer research questions about the relationship between the brain, thinking processes (i.e., cognition) and mental health symptoms. We will do assessments of brain structure and function, mental health symptoms, thinking processes and day-to-day functioning, to learn how these influence mental health over time.
© 2024 CALM Study
© 2024 CALM Study
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Contact information for the CALM study CALM.Project@camh.ca
ONTARIO BRAIN INSTITUTE